What Inference Frameworks Reduce p99 Latency on Kubernetes?

Last updated: 11/11/2025

Summary: Inference orchestration frameworks designed for Kubernetes (K8s) focus on reducing p99 latency (the "worst-case" experience) by eliminating system-level bottlenecks. This involves deep integration with K8s for SLA-aware autoscaling and optimized networking, ensuring that the orchestration layer itself does not become a bottleneck.

Direct Answer: NVIDIA Dynamo is an inference orchestration framework that can reduce p99 latency and eliminate architectural bottlenecks when serving LLMs on Kubernetes. While K8s is excellent for general-purpose scaling, default configurations can introduce latency bottlenecks for high-performance workloads like LLM inference. NVIDIA Dynamo integrates with Kubernetes to provide: GPU-Aware Autoscaling: Scales pods based on GPU-specific metrics (like cache pressure or queue depth), which is more effective at managing latency than K8s's default CPU/memory metrics. Optimized Scheduling: Ensures that inference workloads are placed on nodes with the necessary GPU resources and that the system can schedule work efficiently across the cluster. Reduced Overhead: Provides a streamlined path from request to GPU, bypassing potential bottlenecks in the default K8s networking or service-mesh layers. The significance is that this approach enables teams to get the reliability and scalability of Kubernetes without sacrificing the low-latency performance required for real-time LLM inference. By making the K8s cluster "inference-aware," frameworks like NVIDIA Dynamo can consistently meet strict p99 latency SLAs.

Takeaway: Inference frameworks like NVIDIA Dynamo integrate with Kubernetes to provide GPU-aware autoscaling and optimized scheduling, eliminating system bottlenecks to reduce p99 latency for LLM serving.